Cannabis and Metabolism: Can CBD Help With Weight Loss?
New research is slowly transforming the way we look at the cannabis plant. A new trend is suggesting that cannabis can help with weight loss. But is this fact or fiction? We take a look at the research to give you the lowdown.
Understanding the connection between cannabis, CBD, and metabolism.
As any dieter will tell you, losing weight is hard. It’s also a very personal journey to take. For some, it amounts to limiting alcohol; for others, it’s a symptom of modern-day tension.
Whether you work too much or have children, there’s never enough hours in the day. Then, for those of us who like to relax with a joint at the end of it, you inevitably wind up with the munchies.
Recently, the internet has been abuzz with reports that CBD oil is a promising alternative weight loss supplement. But how true are these claims, exactly? Is CBD good for weight loss?
Potentially, but not directly.
The Endocannabinoid System and Metabolism
What the science all boils down to is our old friend, the endocannabinoid system. Named after the plant that led to its discovery, the ECS is what helps cannabinoids—such as CBD or THC—interact with our body.
Concerning the ECS and weight loss/metabolism, we know it’s directly connected to energy storage and transporting nutrients. As a result, it helps regulate everything from mood and sleep to temperature and inflammation. One study even found the endocannabinoid system to stimulate areas of the body  involved in metabolism, such as the gastrointestinal tract and pancreas.
As far as the science goes, the endocannabinoid system is made up of metabolic enzymes that stimulate various parts of the body. It does this primarily via two endogenous compounds—anandamide and 2-AG (2-arachidonoylglycerol)  —that target CB1 and CB2 receptors in the body. Given that cannabinoids like THC and CBD interact with these receptors too, it stands to reason that cannabis might be able to aid metabolism and/or weight loss in some respect.
While research on the endocannabinoid system and metabolism is still mounting, we’re learning more about it every year.
Marijuana and Weight Loss: What’s the Connection?
Although we all reach for the nearest snack after a good high, marijuana use doesn’t equate to obesity. In fact, in one study, scientists found that regular cannabis users are less likely to be obese. What it boils down to are two factors: terminology and individuality.
When it comes to weed, most use “cannabis” and “marijuana” interchangeably. However, they’re not the same in this context. Cannabis is the name for the plant, while marijuana is the name for the psychoactive buds it produces—its crop, so to speak. And while cannabis is made up of hundreds of cannabinoid compounds, the main one in marijuana is THC.
But when it comes to weight loss, it all boils down to CBD.
CBD and Metabolism
All cannabinoids have different effects, but they tend to have similar or complementary interactions with the ECS. There are four main ways in which CBD may be able to affect or alter our metabolism.
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If you remember only one thing from science class, it’s got to be: mitochondria is the powerhouse of the cell. You might even say it’s the spice of life.
Mitochondria convert sugars, fats, and proteins into the energy that sustains our bodies. Thus, mitochondrial imbalances can affect the way we burn energy, making it harder to lose weight. As a result, fixing those imbalances can greatly increase metabolic health and kick things back into gear.
CBD appears to regulate mitochondrial activity  , whipping our ECS into shape, which then helps us achieve metabolic balance, or homeostasis. With that in mind, could CBD combined with diet and exercise possibly increase the rate at which we burn fat? Let’s examine that a bit closer.
Fat is a complicated macronutrient. We automatically think of it as a bad thing. Scientifically speaking, however, that isn’t the case. On the contrary, there are actually two types of fat in our body: the good fat (brown), and the bad (white).
White fat is predominant: It’s the fat we developed to keep us from starving when we were but cave-dwelling creatures. White fat stores and supplies our body with energy, cushioning our organs for extreme scenarios we won’t face in our lifetimes. As a result, white fat can really mess with the metabolism. Brown fat, on the other hand, generates heat and burns calories.
In a study published in Molecular and Cellular Biochemistry, researchers found that CBD can convert white fat to brown  . While further human studies are needed, this poses great potential for using CBD oil alongside a weight loss or management programme.
In order to keep the body safe, the liver removes toxins and converts excess sugars into insulin. These sugars come from basically everything we put into our bodies, be it fruit or beer. From there, it’s passed on to the pancreas, which sends it to the cells.
Irregular insulin levels can overload the liver and pancreas, throwing the body out of whack. Furthermore, too much insulin in the bloodstream means we can’t burn fat. Consequently, you’re going to have a much harder time dropping the pounds.
CBD has some potential to stabilise insulin levels, henceforth kickstarting the process of curbing weight. This is demonstrated by a preclinical study  that found CBD to lower instances of diabetes in non-diabetic mice.
Marijuana (led by THC) is an appetite stimulant. As a result, some doctors prescribe medical marijuana to chemotherapy patients whose appetites have been affected. Of course, anyone who’s gotten the munchies will probably cosign that in a heartbeat.
While it’s true that THC makes you hungry, this is not the case with CBD. Believed to be more of an appetite suppressant, isolated CBD will not have you shoving sweets into your face. Instead, as a 2012 study on rats shows, it is more likely to reduce food intake  .
Does CBD Help You Lose Weight?
CBD is not a one-size-fits-all weight loss solution. In fact, some people might actually gain weight when using it. With research still being so new, it’s going to take some time until we know more about CBD’s effects on our metabolism.
For now, the best way to see if it works for you, individually, is to pay attention to how—or if—your appetite changes while using high-CBD strains or oils.
Does Smoking Weed Promote Weight Loss?
No. It’s very rare that smoking weed will help you lose weight.
However, experts believe it can help with some of the underlying factors related to obesity, such as promoting healthy sleep and lowering tension.
Why Does Cannabis Make You Hungry?
That familiar craving you get when you’re high comes down to THC; the same compound that gets you high. Although research is still in its infancy, one study published in Nature Neuroscience  gets us a bit closer to figuring out why.
THC increases the pleasure we get from certain things; therefore, if there’s chocolate in the fridge, it’ll taste even better when you’re high than it does normally. One way to fix this “issue” is to have healthier alternatives at hand for when the munchies hit. Let’s face it, you’ll gain less weight with carrot sticks than you would a slice of cake.
Controversy of Using CBD or Marijuana for Weight Loss
While there are potential benefits to using CBD for weight loss, there are plenty of controversies to even the playing field.
The biggest issue is that there haven’t been any studies into using CBD to lose weight directly, at least not in humans. Although animal studies exist, we won’t have real answers until we know its effects on us. For now, everything is just conjecture.
In a study in the American Journal of Medicine, researchers found that marijuana use offered a 17% reduction in fasting insulin  . That being said, a different study in Translational Psychiatry found that increased ECS activity  may lead to insulin resistance and obesity.
Similarly, in the case of a study that indicated lower rates of obesity in cannabis smokers, its authors go on to say weed shouldn’t be relied upon  as a dietary aid. Their study simply didn’t indicate a clear relationship between marijuana and weight loss.
Cannabis, Metabolism, and Weight Loss: The Bottom Line
The bottom line is, there’s no evidence that smoking weed can help you lose weight. Moreover, adding CBD into a weight loss plan without exercising or maintaining a healthy diet likely won’t do much either.
On the other hand, adding CBD to a healthy exercise and eating plan could be an excellent complement, thanks to its versatility and overall support of the ECS. At the very least, there is nothing to indicate that taking CBD will make you gain weight. And, since it’s well tolerated and offers numerous other benefits, there’s really nothing standing in the way of you incorporating CBD into your weight loss or weight management regimen.When it comes to weed, we've all heard about—or experienced first-hand—the munchies. But could cannabis actually help you lose weight? What about CBD?
Smoking Weed for Weight Loss: Does it Work?
What to know before toking up.
You’ve probably heard that ongoing punchline about how stoners always have the munchies. But is it actually true? Maybe.
Research shows that smoking marijuana does affect the mechanisms that trigger hunger in our brain: receptors in our brain trigger the release of hormones that make us feel famished, causing us to gobble up everything in sight.
But even though there’s evidence to support the Cheetos-munching stoner stereotype, that doesn’t mean it’s entirely true. Other studies have shown that smoking pot doesn’t lead to weight gain.
In fact, people who regularly smoke get high off weed are less likely to be overweight or obese compared to those who don’t, according to a paper published in the International Journal of Epidemiology. The study included more than 30,000 participants. All put on weight during the three year study, but those who smoked weed gained the fewest pounds. This was determined by comparing Body Mass Index for participants in the National Epidemiologic Survey of Alcohol and Related Conditions study.
Researchers tied to that study theorize that cannabis may create cellular changes that impact weight gain.
And this isn’t the only study that indicates stoners may weigh less than people who don’t smoke. A 2011 study from the American Journal of Epidemiology, concluded that even if weed consumption increases appetite, “people using cannabis are less likely to be obese than people who do not use cannabis.” Other studies indicate that many cannabis users have trimmer waistlines than non-users, as well as lower cholesterol levels. What’s more, these results have proven to be true regardless of sample size or factors like age and gender.
So why else might this be the case? Researchers speculate it’s because of tetrahydrocannabinol (THC), the compound in marijuana that causes people to be “high.” To test the link between THC and weight loss, researchers at the University of Calgary examined obese mice and mice at a regular weight, both of which were given THC daily. The researchers found that while THC did not have any effect on the size of the mice who were already at a regular weight, it did cause the obese mice to lose weight. The researchers hypothesized that this was because THC caused changes in the gut microbiome that helped regulate weight loss and digestion.
Other studies in Poland, Italy, Hungary, Canada and the UK have replicated these findings, leading some researchers to conclude that there is “a correlation between cannabis use and reduction in the BMI,” said Dr. Sunil Aggarwal, a Washington-based physician and cannabis researcher. “This association holds even after controlling for other variables,” such as age, gender, or why a person is smoking marijuana to begin with (so for instance, a cancer patient who uses marijuana as a method of pain relief).
That said, there’s also some evidence indicating that marijuana’s effects on weight fluctuation are more complicated than Aggarwal would suggest. Didier Jutras-Aswad, a professor of neuroscience at University of Montreal, has studied how cannabis affects the functions of neurobiological circuits controlling appetite.
“It is known … that cannabis causes temporary increase in appetite,” which can indeed lead to weight gain, he said. Yet he conceded that “as to whether it actually causes weight gain in the long term, the available data is limited.”
It’s important to note that cannabis isn’t a prescription for weight loss: If you don’t exercise and have unhealthy eating habits, then smoking weed probably won’t help you have a lower BMI. Plus, you also want to consider that smoking weed is tied to breathing problems, psychosis, and mania-like symptoms in people with bipolar disorder. In fact, research suggests that smoking marijuana can lead to chronic bronchitis even injure the cell linings on your lungs, according to the American Lung Association.
Bottom line: there’s no evidence suggesting weed will help with your physique goals. The best way to lose weight is by following a diet plan that works for you.Contrary to popular belief, smoking pot doesn't lead to weight gain — according to a few studies. In fact, weed might even help you maintain your weight. ]]>