Using CBD to repair Neuro inflammation and Immune Dysregulation
In this episode, Dr. Michael Karlfeldt and Dr. Chris Shade Ph.D. discuss the endocannabinoid system and the effect of CBD on chronic conditions such as Anxiety, ADHD, Autism, Auto-immune conditions such as rheumatoid arthritis, type 1 Diabetes, Hashimoto’s, and even cancer.
Dr. Shade is an expert on the human aspects of mercury exposure, toxicity, and the human detoxification system. He has developed specific clinical analytical techniques for measuring mercury exposure and a system of products to remove metallic and organic toxins by up-regulation of innate detoxification biochemistry.
His current focus is at the intersection of neuro-inflammatory issues, immune dysregulation, toxicity, and infection – specifically how to peel away the layers of overlapping dysfunction in the sick individual until you get to a point at which the system rights itself.
CBD works on a number of different levels, like a symphony. This is the most exciting supplement for us in the last 30 years in functional and integrative medicine.
In this episode of HealthMade radio, Dr. Karlfeldt discusses the impact of CBD as a powerful tool to support homeostasis in the body.
- The ability of CBD to modulate balance throughout various body systems
- Using CBD as a backdrop of any de-toxic protocol
- Immuno-modulating effect of CBD for autoimmune conditions such as rheumatoid arthritis, Type1 Diabetes, Hashimotos.
- Using CBD to calm the fire of neuroinflammation (while you try to get to the root causes of those disorders) Autism, ADD, ADHD the impact of CBD on “neuro-inflamed” conditions
- The future of Natural Integrative medicine combining CBD
- Broad-spectrum CBD and CBD blends anti-inflammatory compounds such as Boswellia, Cinnamon, Cloves and more that activate CB2 receptors to achieve entourage effects
- CBD and cancer
The endocannabinoid system (ECS) is a complex cell-signaling system identified in the early 1990s by researchers exploring THC, a well-known cannabinoid. Cannabinoids are compounds found in cannabis. While humans have just discovered this deeply integrated human system, its been around since the beginning of time, explains Dr. Chris Shade Ph.D.
Endocannabinoids, also called endogenous cannabinoids, are molecules made by your body. They’re similar to cannabinoids, but they’re produced by your body.
Experts have identified two key endocannabinoids so far:
- anandamide (AEA)
- 2-arachidonoylglyerol (2-AG)
These help keep internal functions running smoothly. Your body produces them as needed, making it difficult to know what typical levels are for each.
These receptors are found throughout your body. Endocannabinoids bind to them in order to signal that the ECS needs to take action.
There are two main endocannabinoid receptors:
- CB1 receptors, which are mostly found in the central nervous system
- CB2 receptors, which are mostly found in your peripheral nervous system, especially immune cells
Endocannabinoids can bind to either receptor. The effects that result depend on where the receptor is located and which endocannabinoid it binds to.
CBD is coming from industrial hemp, which is the THC is bred out of it, and you’re left with another component that is big in the resins of cannabis, and it’s called cannabidiol. It’s chemically different than THC, and its physiological effects are vastly different, and they seem almost magical when you look at so many … At the variety of things that they do for you, but they don’t get you high.
CBD provides what Dr. Shade refers to as “Neuro-endo-immune poise, or balance”. Neuro means neurotransmitters. Endo is endocrine or hormone, and immune is obvious. It’s the immune system. Neurologically is how we used it the most, for damping neuro-inflammation. Focusing on the root cause of the problem and supporting the body in detoxification.
Symptomology neuro-inflammation, your autonomic nervous system becomes sympathetically dominant. You’ve got overactivity of glutamate receptors, there’s activation of the immune system in the brain called the microglia, and they’re sort of at war with the glutamate receptors.
That’s causing anxiety first, then brain fog, then a disruption with the autonomic nervous system. You’re moving resources and blood in wrong ways throughout the body, and this acts to just stabilize all of that.
It will block the excitation of the microglia. It will stabilize the glutamate receptor. That will result in a neuro-stabilization. Your neurotransmitter balance between glutamate and GABA gets balanced. Your autonomic nervous system balance between parasympathetic and sympathetic gets balanced.
But that starts cascading down even farther into the body, and we start to look at really what homeostasis or balance of the biology is, and it’s a set of reactions that all have these yin-yang poles, which you want to sit in the middle of and take forays in the yin or yang as needed to handle different perturbations, but you always want to come back to the poise of the center, and CBD is always bringing that back to the middle.
Cannabidiolin in CBD have an effect of balancing and calming the mind, but they have so many different therapeutic benefits, and it’s really just getting people out of the fear of the evil weed, into this wonderful, medicinal plant and all the uses it has.
More about expert Chris Shade Ph.D.
Born in a toxic steel town, Dr. Shade created Quicksilver Scientific to combat the environmental toxicity he personally experienced. Inspired by philosophy, guided by science, and driven to create, he patented a mercury speciation diagnostic process to analyze human toxicity. In addition, he created Quicksilver Delivery Systems® nanoparticle technology to increase the bioavailability of supplements and protocols leading to higher efficacy products without the prick of a needle.
For more than a decade, Dr. Shade has worked alongside practitioners to fine-tune a system and its applications to restore, maintain, and advance health. To this day, Dr. Shade develops all of our products and protocols and leads the R&D team at Quicksilver Scientific in both our lab and testing facility. Dr. Shade is regularly sought out to speak as an educator on the topics of mercury, environmental toxicities, neuroinflammation, immune dysregulation, and the human detoxification system for practitioners and patients in the United States and internationally. He has helped corporate executives, professional athletes, celebrities, children with autism, patients with chronic immune disorders and more. He strives to evolve the way the medical industry delivers care, and he is perpetually broadening the way the world understands health.
Quicksilver Scientific is a leading manufacturer of advanced nutritional systems with a focus on detoxification. We specialize in superior liposomal delivery systems and heavy metal testing to support optimal health. Our advanced liposomal supplements are highly absorbable, and support the body in the elimination of ubiquitous toxins, enabling you to achieve your genetic potential. At Quicksilver Scientific, we are passionate about health and well-being, and are committed to improving the lives of everyone we touch.
Using CBD to repair Neuro inflammation and Immune Dysregulation In this episode, Dr. Michael Karlfeldt and Dr. Chris Shade Ph.D. discuss the endocannabinoid system and the effect of CBD on